MOTS-C

MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a 16-amino-acid mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region. It has CAS number 1627580-64-6, molecular formula C101H152N28O22S2 and molecular weight 2174.6 g/mol. Kyrolabs supplies it as a lyophilised reference compound for laboratory research only.

MOTS-c is not a controlled drug under the Misuse of Drugs Act 1971 and is not a scheduled substance. It is legal to supply in the UK as a research chemical for laboratory use only. It is not authorised as a medicine, cannot be sold or purchased for human or veterinary consumption, and the buyer is responsible for lawful handling and storage.

No. MOTS-c is supplied strictly for laboratory research use only. It is not a medicine, not a supplement and not for human or veterinary consumption. No human or veterinary application is intended or implied, and it must not be administered to people or animals.

The literature investigates MOTS-c as a signalling peptide in the mitochondrial and AMPK research pathway, in laboratory and animal models. These are research-context observations only and do not establish any human benefit or effect. The mechanistic detail and cited studies are covered in our MOTS-c research monograph linked from the product page.

The MOTS-c amino-acid sequence is Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg, a 16-residue peptide. It carries the molecular formula C101H152N28O22S2 with a molecular weight of 2174.6 g/mol, consistent with its mitochondrial-derived origin.

MOTS-c is identified by CAS number 1627580-64-6 and PubChem CID 146675088. Its molecular formula is C101H152N28O22S2 and its molecular weight is 2174.6 g/mol. These identifiers let researchers cross-reference the material against public chemical databases such as PubChem.

No. Purity and identity vary by supplier and batch, which is why analytical documentation matters. Kyrolabs releases each MOTS-c batch only after independent testing showing 99% or greater purity by HPLC and identity confirmed against the expected mass. A certificate of analysis is provided so you can verify the specific lot.

Yes. Every batch of MOTS-c ships with a certificate of analysis reporting purity (99% or greater by HPLC) and confirmed identity against the expected mass for C101H152N28O22S2. You can review CoA documentation on our CoA page to confirm the lot matches the stated identity before any research use.

MOTS-c is supplied as a white to off-white lyophilised powder. For bench work it is reconstituted in a suitable solvent such as bacteriostatic water, which Kyrolabs also stocks. It is a research reagent prepared for laboratory use; reconstitution is a bench step and the material is not for administration to humans or animals.

Store the lyophilised MOTS-c powder at -20C, kept dry and protected from light. Once reconstituted, hold the solution at 2-8C. Proper storage preserves the integrity of the peptide for laboratory research. The material is for research use only, not for human or veterinary use.

MOTS-c is a peptide: a 16-amino-acid chain (sequence Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg) derived from the mitochondrial 12S rRNA region. It is not a steroid or a small-molecule drug. Its formula C101H152N28O22S2 and weight 2174.6 g/mol reflect its peptide structure.

MOTS-c is a mitochondrial-derived peptide studied in the AMPK research pathway, which is a distinct molecule from incretin and amylin-class research compounds such as retatrutide and cagrilintide. Each is a different chemical with its own identifiers and is supplied separately for laboratory research use only, not for human use.

Kyrolabs supplies MOTS-c in the UK as a research chemical, despatched from the UK with a certificate of analysis for each batch. It is sold for laboratory research use only, not for human or veterinary consumption. See the metabolic research category for related reference compounds in the catalogue.